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MF C27H35N5MW 429,60
Small molecule capable of reducing GLI-mediated transcription and endogenous Hedgehog (Hh) signaling (IC50 value ca 5 µM). In vivo, GANT61 suppressed human tumor cell growth until no tumor was palpable.
KEYWORDS: GANT61 | supplier | GLI inhibitor | NSC 136476 | GANT-61 | NSC136476 | CAS [500579-04-4] | Hedgehog | GLI1 | GLI2 | Transcription Factor | Hh | Hedgehog signaling | cancer | cytotoxic | AML | tumor | apoptosis | leukemia
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
Download the Axon Ligands™ catalogue Spring 2016 Edition
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