LY 2955303 dihydrochloride

Based on 1 publications in PubMed 9 10 1

Axon 2637

CAS [2469014-43-3]

MF C36H42N4O3.2HCl
MW 651.67

Purity: 99%
Soluble in DMSO

LY 2955303 dihydrochloride

Description

Potent and selective retinoic acid receptor gamma (RARγ) antagonist (Ki values >1700 nM, >2980 nM, and 1.1 nM for RARα, RARβ, and RARγ, respectively) for the treatment of osteoarthritis joint pain.

NE Hughes et al. Identification of potent and selective retinoic acid receptor gamma (RARγ) antagonists for the treatment of osteoarthritis pain using structure based drug design. Bioorg Med Chem Lett. 2016 Jul 15;26(14):3274-7.

Potent and selective RARγ antagonist for the treatment of osteoarthritis pain

Chemical name

4-(5-(3,5-ditert-butylphenyl)-1-(4-(4-methylpiperazine-1-carbonyl)phenyl)-1H-pyrazol-3-yl)benzoic acid dihydrochloride

Parent CAS No.

[1433497-19-8]

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Size	Unit Price	Stock
5 mg	€145.00	In Stock
25 mg	€545.00	In Stock

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LY 2955303 dihydrochloride

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LY 2955303 dihydrochloride

Description

Chemical name

Parent CAS No.

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