YJC-10592

Based on 15 reference(s) in Google Scholar 8 10 15

Axon 2636

CAS [1226894-87-6]

MF C27H31ClF3N5O3
MW 566.01

  • Purity: 98%
  • Optical purity: Optically pure
  • Soluble in DMSO
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YJC-10592

Description

YJC-10592 is a CC chemokine receptor 2 (CCR2) antagonist (IC50 value 1.12 μM), which also showed excellent inhibitory activity in the calcium assay (IC50 value 1.7 nM), and good potency in the chemotaxis assay (IC50 value 23 nM). In rats, YJC-10592 showed dose-dependent pharmacokinetics and low F value due to slower elimination and incomplete absorption.

KEYWORDS: YJC-10592 | supplier | CCR2 antagonist | YJC10592 | YJC 10592 | CAS [1226894-87-6] | Chemokine | Antagonist | Receptors | CCR2 | CCR 2

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Size Unit Price Stock
5 mg €145.00 In Stock
25 mg €580.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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