MC70 hydrochloride

Based on 43 reference(s) in Google Scholar 9 10 43

Axon 2591

CAS [2108830-71-1]

MF C24H25NO3.HCl
MW 411.92

  • Purity: 98%
  • Soluble in DMSO

MC70 hydrochloride


Potent P-gp inhibitor with good selectivity towards BCRP pump (EC50 values 0.05 μM, 0.69 μM, 9.3 μM, and 73 μM for Caco-2, MDR1, MRP1, and BCRP inhibition, respectively), with potential as novel anticancer agent with both cytostatic and cytotoxic characteristics. MC70, as an inhibitor of the ABC transporter ABCB1 (aka MDR1), potentiates Doxorubicin efficacy in colon and breast cancer in vitro treatment.

*Sold in collaboration with Biofordrug srl

KEYWORDS: MC70 hydrochloride | supplier | P-gp inhibitor | MC-70 | MC 70 | CAS [2108830-71-1] | [1031367-64-2] | PGP | ABC transporter | ABCB1 | MDR1 | BCRP | Caco-2 | breast cancer | Non Selective | P-glycoprotein | Inhibitor | Proteins

Size Unit Price Stock
10 mg €125.00 In Stock
50 mg €450.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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