BTB 1 - NSC 156750 | NSC 658180

Based on 16 reference(s) in Google Scholar 9 10 16

Axon 2407

CAS [86030-08-2]

MW 297.71

  • Purity: 99%
  • Soluble in DMSO and Ethanol



The first small molecule reversible inhibitor of the mitotic motor protein Kif18A (IC50 value 1.69 µM for inhibition of Kif18A ATPase activity) that acts in an ATP-competitive and microtubule (Mt) uncompetitive manner.

BTB-1 (aka NSC 156750 or NSC 658180) was previously tested and found to inhibit HIV-1 replication (IC50 value 29.2 µM in cellular anti-HIV-1 assay), yet BTB1 proved to be cytotoxic at low micromolar concentrations.

Size Unit Price Stock
10 mg €70.00 In Stock
50 mg €210.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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