BTB 1 - NSC 156750 | NSC 658180

Based on 16 reference(s) in Google Scholar 9 10 16

Axon 2407

CAS [86030-08-2]

MF C12H8ClNO4S
MW 297.71

  • Purity: 99%
  • Soluble in DMSO and Ethanol

BTB 1

Description

The first small molecule reversible inhibitor of the mitotic motor protein Kif18A (IC50 value 1.69 µM for inhibition of Kif18A ATPase activity) that acts in an ATP-competitive and microtubule (Mt) uncompetitive manner.

BTB-1 (aka NSC 156750 or NSC 658180) was previously tested and found to inhibit HIV-1 replication (IC50 value 29.2 µM in cellular anti-HIV-1 assay), yet BTB1 proved to be cytotoxic at low micromolar concentrations.

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10 mg €70.00 In Stock
50 mg €210.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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