Order

Size
Price
Stock
Qty

IMM 01

Axon 2406
CAS:  218795-74-5
Purity:  99%
  • Soluble in DMSO
  • MF:  C12H17N3O2S
  • MW:  267.35

Description

Small-molecule agonist of mammalian Diaphanous (mDia)-related formins that inhibited DID–DAD binding (IC50 value 140 nM). IMM-01 induced filopodia-like structures similar to those observed in cells expressing constitutively active mDia1 or mDia2. Moreover, IMM01 triggered actin assembly and microtubule stabilization consistent with formin activation in NIH 3T3 cells.

More Information

Parent CAS No. 218795-74-5
Chemical Name N-tert-butyl-2-(2,4-dihydroxybenzylidene)hydrazinecarbothioamide
SMILES N(C(=S)NC(C)(C)C)/N=C/C1=CC=C(O)C=C1O
MFCD N.A.
InChi InChI=1S/C12H17N3O2S/c1-12(2,3)14-11(18)15-13-7-8-4-5-9(16)6-10(8)17/h4-7,16-17H,1-3H3,(H2,14,15,18)/b13-7+
InChiKey LTFUAYRGVLQXKC-NTUHNPAUSA-N
CID 135445526
Short Description mDia agonist

Related Products

AXON ID NAME FROM PRICE
1233 Combretastatin-A4

From $93.50

1310 Myoseverin

From $137.50

1650 HTI 286

From $154.00

1804 Wiskostatin

From $115.50

2281 FIPI hydrochloride

From $110.00

2299 Remodelin

From $99.00

2439 Dimethylenastron

From $115.50

2446 Ispinesib

From $121.00

Loading...