IMM 01

Based on 14 reference(s) in Google Scholar 8 10 14

Axon 2406

CAS [218795-74-5]

MF C12H17N3O2S
MW 267.35

  • Purity: 99%
  • Soluble in DMSO

IMM 01

Description

Small-molecule agonist of mammalian Diaphanous (mDia)-related formins that inhibited DID–DAD binding (IC50 value 140 nM). IMM-01 induced filopodia-like structures similar to those observed in cells expressing constitutively active mDia1 or mDia2. Moreover, IMM01 triggered actin assembly and microtubule stabilization consistent with formin activation in NIH 3T3 cells.
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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