JavaScript seems to be disabled in your browser. You must have JavaScript enabled in your browser to utilize the functionality of this website.
There are no items in your shopping cart
Featured Products
Axon 2385
CAS [1214265-58-3]
MF C25H29ClN6O3MW 496.99
Specific dual inhibitor of NUAK1 (aka ARK5) and NUAK2 (aka SNARK; IC50 values 20 nM and 100 nM, respectively) with no significant inhibitory effect on a panel of 139 other kinases tested, including ten other AMPK-related kinases. WZ4003 suppressed MYPT1 phosphorylation in a dose-dependent manner, and inhibited cell proliferation, invasion and migration in vivo. Although WZ 4003 is a close analogue of WZ 4002 (Axon 1506), it shows no affinity for the EGFR (Kd value 14 µM)
N-(3-(5-chloro-2-(2-methoxy-4-(4-methylpiperazin-1-yl)phenylamino)pyrimidin-4-yloxy)phenyl)propionamide
[1214265-58-3]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
* Required Fields