GSK 2033

Based on 8 reference(s) in Google Scholar 9 10 8

Axon 2363

CAS [1221277-90-2]

MF C29H28F3NO5S2
MW 591.66

  • Purity: 100%
  • Soluble in DMSO

GSK 2033


The first potent cell-active LXR antagonist (IC50 value 31.6 nM for LXRβ binding). In intact cells stimulated with LXR agonist, GSK 2033 showed a dose-dependent reduction in the expression of the ATP-binding cassette transporter A1 (ABCA1) in THP-1 cells and SREBP-1c in HepG2 cells. A useful chemical probe to explore the cell biology of the LXR receptor.

KEYWORDS: GSK 2033 | supplier | LXR antagonist | GSK2033 | CAS [1221277-90-2] | Metabolism | LXR | Agonist | ATP-binding cassette transporter A1 | ABCA1 | nuclear receptor | NR | lipid | homeostasis | cholesterol

Size Unit Price Stock
5 mg €105.00 In Stock
25 mg €365.00 In Stock
Special Offers
Size Unit Price Stock
2 x 5 mg €150.00 In Stock
2 x 25 mg €540.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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