Endoxifen - 4OHNDtam | N-Desmethyl-4-hydroxytamoxifen

Based on 14 reference(s) in Google Scholar 8 10 14

Axon 2190

CAS [110025-28-0]

MF C25H27NO2
MW 373.49

  • Purity: 99%
  • Soluble in 0.1N HCl(aq) and DMSO



Metabolite of Tamoxifen and a selective estrogen receptor modulator (SERM); Potently inhibits the growth of estrogen-stimulated BT474 cells (IC50: 54 nM). Approximately 100-fold more potent as an antagonist of the ERα than the parent drug. Drug for the treatment of estrogen receptor (ER) positive breast cancer.
The water soluble hydrochloride salt Endoxifen hydrochloride is available as Axon 2707. The more active isomer, Z-Endoxifen, is available as Axon 2221.

KEYWORDS: Endoxifen | supplier | SERM | 4OHNDtam | N-Desmethyl-4-hydroxytamoxifen | CAS [110025-28-0] | Estrogen | Selective Estrogen Receptor | Modulator | Nuclear receptor | metabolite | ER positive breast cancer | Tamoxifen

Size Unit Price Stock
10 mg €125.00 In Stock
50 mg €450.00 In Stock
Special Offers
Size Unit Price Stock
2 x 10 mg €200.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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