CID 1067700 - ML282

Based on 14 reference(s) in Google Scholar 8 10 14

Axon 2184

CAS [314042-01-8]

MF C18H18N2O4S2
MW 390.48

  • Purity: 99%
  • Soluble in DMSO

CID 1067700


First inhibitor of Rab7 GTPase exhibiting significant inhibitory potency on Rab7 nucleotide binding with nanomolar inhibitor (Ki) values and an inhibitory response of ≥97% for BODIPY-GTP and BODIPYGDP binding (Ki values 13 nM and 19 nM, and EC50 values 11 and 21 nM, respectively). CID 1067700 is a competitive guanine nucleotide binding inhibitor characterized for the Ras-super family of GTPases.

Size Unit Price Stock
10 mg €125.00 In Stock
50 mg €450.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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