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PF 5274857 hydrochloride - PF 05274857 hydrochloride

Based on 20 reference(s) in Google Scholar 80 100 20

Axon 2027

CAS [1373615-35-0]

MF C20H25ClN4O3S.HCl
MW 473.42

  • Purity: 99%
  • Soluble in water and DMSO

PF 5274857 hydrochloride

Description

Potent and selective smoothened (SMO) antagonist with Ki value of 4.6 nM; a potentially attractive clinical candidate for the treatment of tumor types including brain tumors and brain metastasis driven by an activated Hh pathway
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Size Unit Price Stock
5 mg €95.00 In Stock
25 mg €335.00 In Stock
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Size Unit Price Stock
2 x 5 mg €140.00 In Stock
2 x 25 mg €560.00 In Stock
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Related Products

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1938 MRT 10 Smoothened (SMO) receptor antagonist €125.00
2196 LY 2940680 Small-molecule antagonist of the Smoothened (SMO) receptor €120.00
2356 BMS 833923 Oral antagonist of the Hedgehog signaling component Smoothened (SMO) €75.00
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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