Estetrol

Based on 20 reference(s) in Google Scholar 80 100 20

Axon 1926

CAS [15183-37-6]

MF C18H24O4
MW 304.38

  • Purity: 100%
  • Optical purity: Optically pure
  • Soluble in DMSO

Estetrol

Description

Estetrol has a relatively moderate affinity for human estrogen α receptor (ERα) and estrogen β receptor (ERβ), with Ki values of 4.9 nmol/l and 19 nmol/l, respectively. Nevertheless, at a concentration of 10 μmol/l, Estetrol shows nearly no affinity for a wide range of >120 other receptors, among them the glucocorticoid, progesterone and testosterone receptors. An estrogen steroid and a metabolite of Estradiol
Estrogen receptor agonist (four- to five-fold preference for the Erα)

Chemical name

(8R,9S,13S,14S,15R,16R,17R)-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,15,16,17-tetraol

Parent CAS No.

[15183-37-6]

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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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