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Purmorphamine

Axon 1690
CAS:  483367-10-8
Purity:  99%
  • Soluble in DMSO
  • MF:  C31H32N6O2
  • MW:  520.62

Description

Hedgehog (Hh) agonist that directly targets Smoothened (SMO) transmembrane protein. Purmorphamine up-regulates gene expression of mediators of Hh pathway, SMO, PTCH1, GLI1, and GLI2, and induces osteoblast differentiation of multipotent mesenchymal progenitor cells and lineage-committed preosteoblasts.

More Information

Certificate of Analysis

Material Safety Data Sheet

Parent CAS No. 483367-10-8
Chemical Name 9-cyclohexyl-N-(4-morpholinophenyl)-2-(naphthalen-1-yloxy)-9H-purin-6-amine
SMILES C12N=C(OC3C=CC=C4C=CC=CC=34)N=C(NC3C=CC(=CC=3)N3CCOCC3)C=1N=CN2C1CCCCC1
MFCD MFCD09037557
InChi InChI=1S/C31H32N6O2/c1-2-9-25(10-3-1)37-21-32-28-29(33-23-13-15-24(16-14-23)36-17-19-38-20-18-36)34-31(35-30(28)37)39-27-12-6-8-22-7-4-5-11-26(22)27/h4-8,11-16,21,25H,1-3,9-10,17-20H2,(H,33,34,35)
InChiKey FYBHCRQFSFYWPY-UHFFFAOYSA-N
CID 5284329
Short Description SMO agonist

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