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NVP-LDE225 - LDE 225 | Sonidegib | Erismodegib

Based on 20 reference(s) in Google Scholar 80 100 20

Axon 1619

CAS [956697-53-3]

MF C26H26F3N3O3
MW 485.50

  • Purity: 98%
  • Soluble in DMSO

NVP-LDE225

Description

Potent, selective and orally bioavailable Smoothened (SMO) antagonist (IC50: 50 nM); it inhibits hedgehog (Hh) signaling pathway via antagonism of the Smoothened receptor (SMO)
Order
Size Unit Price Stock
5 mg €85.00 In Stock
25 mg €285.00 In Stock
Special Offers
Size Unit Price Stock
2 x 5 mg €120.00 In Stock
2 x 25 mg €400.00 In Stock
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2196 LY 2940680 Small-molecule antagonist of the Smoothened (SMO) receptor €120.00
2356 BMS 833923 Oral antagonist of the Hedgehog signaling component Smoothened (SMO) €75.00
2325 WAY 316606 hydrochloride Potent inhibitor of sFRP-1 that stimulates Wnt signaling €85.00
2642 GANT61 Inhibitor of GLI-mediated transcription and Hedgehog (Hh) signaling €120.00
2654 JK184 Hedgehog (Hh) signaling pathway antagonist with antiproliferative activity €80.00

The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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