SB 265610

Based on 16 reference(s) in Google Scholar 9 10 16

Axon 1559

CAS [ 211096-49-0]

MF C14H9BrN6O
MW 357.16

  • Purity: 99%
  • Soluble in DMSO

SB 265610

Description

Potent allosteric, inverse agonist/antagonist at the human chemokine CXCR2 receptor. SB-265610 antagonizes rat cytokine-induced neutrophil chemoattractant-1 (CINC-1)-induced calcium mobilization, and rat neutrophil chemotaxis in a concentration-dependent manner (IC50 values 3.7 nM and 70 nM, respectively).

KEYWORDS: SB 265610 | supplier | CXCR2 antagonist | SB265610 | CAS [ 211096-49-0] | Chemokine | Inverse agonist | Antagonist | C-X-C | neutrophil | chemotaxis | calcium mobilization | GPCR

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Size Unit Price Stock
5 mg €95.00 In Stock
25 mg €330.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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