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Featured Products
Axon 1559
CAS [211096-49-0]
MF C14H9BrN6OMW 357.16
Potent allosteric, inverse agonist/antagonist at the human chemokine CXCR2 receptor. SB-265610 antagonizes rat cytokine-induced neutrophil chemoattractant-1 (CINC-1)-induced calcium mobilization, and rat neutrophil chemotaxis in a concentration-dependent manner (IC50 values 3.7 nM and 70 nM, respectively).
KEYWORDS: SB 265610 | supplier | CXCR2 antagonist | SB265610 | CAS [ 211096-49-0] | Chemokine | Inverse agonist | Antagonist | C-X-C | neutrophil | chemotaxis | calcium mobilization | GPCR
Urea, N-(2-bromophenyl)-N'-(7-cyano-1H-benzotriazol-4-yl)-
[211096-49-0]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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