BZ, γ-Secretase Inhibitor - Compound E

Based on 16 reference(s) in Google Scholar 9 10 16

Axon 1487

CAS [209986-17-4]

MF C27H24F2N4O3
MW 490.50

  • Purity: 99%
  • Optical purity: Optically pure
  • Soluble in DMSO

BZ, γ-Secretase Inhibitor


Very potent and cell-permeable inhibitor of γ-secretase (GSI); potently inhibits Notch processing (IC50 values to be 2.2 nM in SupT1 cells); inhibits β-ammyloid production in cell culture with an IC50 of 0.3 nM.

KEYWORDS: γ-Secretase Inhibitor BZ | supplier | γ-Secretase inhibitor | Compound E | CAS [209986-17-4] | Amyloids | γ Secretase | γ-Secretase inhibitor (GSI) | Inhibitor | Enzymes

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1 mg €85.00 In Stock
5 mg €215.00 In Stock
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Size Unit Price Stock
2 x 1 mg €140.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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