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Celiprolol hydrochloride
- Parent CAS: 56980-93-9
- Soluble in water and DMSO
- MF: C20H33N3O4.HCl
- MW: 415.95
Description
More Information
| Parent CAS No. | 56980-93-9 |
|---|---|
| Chemical Name | 3-[3-Acetyl-4-(3-tert-butylamino-2-hydroxy-propoxy)-phenyl]-1,1-diethyl-urea hydrochloride |
| SMILES | C(COC1C(C(C)=O)=CC(NC(=O)N(CC)CC)=CC=1)(O)CNC(C)(C)C.Cl |
| MFCD | MFCD00941500 |
| InChi | InChI=1S/C20H33N3O4.ClH/c1-7-23(8-2)19(26)22-15-9-10-18(17(11-15)14(3)24)27-13-16(25)12-21-20(4,5)6;/h9-11,16,21,25H,7-8,12-13H2,1-6H3,(H,22,26);1H |
| InChiKey | VKJHTUVLJYWAEY-UHFFFAOYSA-N |
| CID | 42373 |
| Short Description | β2 antagonist |
References
- Y Liao et al. Celiprolol, A Vasodilatory ß-Blocker, Inhibits Pressure Overload–Induced Cardiac Hypertrophy and Prevents the Transition to Heart Failure via Nitric Oxide–Dependent Mechanisms in Mice. Circulation. 2004, 110, 692-699.
- FS Caruso et al. Effect of celiprolol, a new beta 1-alpha 2 blocker, on the cardiovascular response to exercise. J. Clin. Pharmacol. 1986; 26, 32-38.
- M Cazzola et al. Comparison of the Effects of Single Oral Doses of Nebivolol and Celiprolol on Airways in Patients With Mild Asthma. Chest. 2000, 118, 1322-1326.
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