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Isoclozapine
- Soluble in DMSO
- MF: C18H19ClN4
- MW: 326.82
Description
Isoclozapine is a 2-chloro analogue of clozapine (Axon 1146) with a distinctly typical antipsychotic-like profile. It is useful as a comparator compound for separating typical and atypical antipsychotic pharmacology.
Comparing isoclozapine with clozapine can help identify receptor interactions associated with atypical antipsychotic activity. Isoclozapine is therefore relevant to structure-activity and receptor-profile studies in CNS drug discovery.
Key Features
- 2-Chloro analogue of clozapine
- Typical antipsychotic-like profile
- Useful comparator to clozapine
- Supports antipsychotic structure-activity research
Applications
- Typical versus atypical antipsychotic comparison
- Clozapine analogue profiling
- Dopamine and serotonin receptor research
- CNS medicinal chemistry studies
More Information
| Parent CAS No. | 1977-08-8 |
|---|---|
| Chemical Name | 2-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine |
| MFCD | MFCD01730996 |
| Short Description | Typical antipsychotic |
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