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Clozapine
- Soluble in DMSO
- MF: C18H19ClN4
- MW: 326.82
Description
Clozapine is an atypical antipsychotic research compound with broad activity across dopaminergic, serotonergic, muscarinic, adrenergic and histaminergic receptors. It is a key reference compound for schizophrenia and antipsychotic mechanism studies.
Clozapine is often used to compare atypical versus typical antipsychotic receptor profiles and to study multi-target CNS pharmacology. Its clinical use is limited by serious adverse effects, but it remains an important research standard for antipsychotic efficacy mechanisms.
Key Features
- Atypical antipsychotic reference compound
- Broad multi-receptor pharmacology
- Distinct profile compared with typical antipsychotics
- Relevant to treatment-resistant schizophrenia mechanism research
Applications
- Antipsychotic receptor profiling
- Dopamine-serotonin interaction studies
- Schizophrenia pathway research
- Comparative atypical versus typical antipsychotic studies
More Information
| Parent CAS No. | 5786-21-0 |
|---|---|
| Chemical Name | 8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine |
| SMILES | N1C2C=CC=CC=2C(N2CCN(C)CC2)=NC2C=C(Cl)C=CC1=2 |
| MFCD | MFCD00153785 |
| InChi | InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 |
| InChiKey | QZUDBNBUXVUHMW-UHFFFAOYSA-N |
| CID | 135398737 |
| Short Description | Atypical antipsychotic |
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