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IDO2 inhibitor compound 22
- Soluble in DMSO
- MF: C21H21BrN10O3
- MW: 541.36
Description
IDO2 inhibitor compound 22 is a first selective IDO2 inhibitor with an IC50 value of 112 nM. Treatment with IDO2 inhibitor compound 22 alleviated disease severity and reduced inflammatory cytokines in both the collagen-induced arthritis (CIA) mice model and adjuvant arthritis (AA) rat model.
More Information
| Parent CAS No. | 2803768-09-2 |
|---|---|
| Chemical Name | (Z)-N-((1-(2-(4-(N-(3-Bromobenzyl)-N'-hydroxycarbamimidoyl)-1,2,5-oxadiazol-3-ylamino)ethyl)-1H-1,2,3-triazol-4-yl)methyl)picolinamide |
| Short Description | IDO2 inhibitor |
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