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Salubrinal

Axon 4249
CAS:  405060-95-9
Purity:  98%
  • Soluble in DMSO
  • MF:  C21H17Cl3N4OS
  • MW:  479.81

Description

Salubrinal is a selective inhibitor of cellular complexes that dephosphorylate eukaryotic translation initiation factor 2 subunit α (eIF2α). Salubrinal also blocks eIF2a dephosphorylation mediated by a herpes simplex virus protein and inhibits viral replication.

More Information

Parent CAS No. 405060-95-9
Chemical Name N-[2,2,2-Trichloro-1-(quinolin-8-ylaminocarbamthioyl)ethyl]-(2E)-3-phenylprop-2-enamide
SMILES C(=S)(NC1=C2N=CC=CC2=CC=C1)NC(C(Cl)(Cl)Cl)NC(=O)/C=C/C1=CC=CC=C1
MFCD MFCD00548612
InChi InChI=1S/C21H17Cl3N4OS/c22-21(23,24)19(27-17(29)12-11-14-6-2-1-3-7-14)28-20(30)26-16-10-4-8-15-9-5-13-25-18(15)16/h1-13,19H,(H,27,29)(H2,26,28,30)/b12-11+
InChiKey LCOIAYJMPKXARU-VAWYXSNFSA-N
CID 5717801
Short Description eIF2α dephosphorylation inhibitor

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