GSK1904529A
Axon 3830
CAS:
1089283-49-7
Purity:
99%
- Soluble in DMSO
- MF: C44H47F2N9O5S
- MW: 851.96
Description
GSK1904529A is a potent, selective and orally active inhibitor of the insulin-like growth factor-1 receptor (IGF-1R) with IC50 values of 27 and 25 nM for IGF-IR and IR (Insulin Receptor), respectively.
More Information
| Parent CAS No. | 1089283-49-7 |
|---|---|
| Chemical Name | N-(2,6-difluorophenyl)-5-(3-(2-(5-ethyl-2-methoxy-4-(4-(4-(methylsulfonyl)piperazin-1-yl)piperidin-1-yl)phenylamino)pyrimidin-4-yl)imidazo[1,2-a]pyridin-2-yl)-2-methoxybenzamide |
| extra_info | Sold in collaboration with Chemietek |
| SMILES | C1C(CC)=C(N2CCC(N3CCN(S(C)(=O)=O)CC3)CC2)C=C(OC)C=1NC1N=CC=C(C2=C(C3C=CC(OC)=C(C(=O)NC4C(F)=CC=CC=4F)C=3)N=C3C=CC=CN23)N=1 |
| MFCD | N.A. |
| InChi | InChI=1S/C44H47F2N9O5S/c1-5-28-26-35(38(60-3)27-36(28)53-19-15-30(16-20-53)52-21-23-54(24-22-52)61(4,57)58)49-44-47-17-14-34(48-44)42-40(50-39-11-6-7-18-55(39)42)29-12-13-37(59-2)31(25-29)43(56)51-41-32(45)9-8-10-33(41)46/h6-14,17-18,25-27,30H,5,15-16,19-24H2,1-4H3,(H,51,56)(H,47,48,49) |
| InChiKey | MOSKATHMXWSZTQ-UHFFFAOYSA-N |
| CID | 25124816 |
| Short Description | IGF-1R inhibitor |
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