Order

Size
Price
Stock
Qty

GSK1278863

 - Daprodustat
Axon 3615
CAS:  960539-70-2
Purity:  99%
  • Soluble in 0.1N NaOH(aq), DMSO and EtOH
  • MF:  C19H27N3O6
  • MW:  393.43

Description

GSK1278863 is a potent, selective and orally active inhibitor of all three HIF prolyl hydroxylase isozymes, PHD1, PHD2, and PHD3 with IC50 values of 3.5, 22.2 and 5.5 nM, respectively.

More Information

Parent CAS No. 960539-70-2
Chemical Name 2-(1,3-Dicyclohexyl-6-hydroxy-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxamido)acetic acid
SMILES C1C(N2C(=O)N(C3CCCCC3)C(O)=C(C(=O)NCC(=O)O)C2=O)CCCC1
MFCD MFCD29924726
InChi InChI=1S/C19H27N3O6/c23-14(24)11-20-16(25)15-17(26)21(12-7-3-1-4-8-12)19(28)22(18(15)27)13-9-5-2-6-10-13/h12-13,26H,1-11H2,(H,20,25)(H,23,24)
InChiKey NVTKJBXOBFRPLQ-UHFFFAOYSA-N
CID 24831508
Short Description HIF-PHD inhibitor

Related Products

AXON ID NAME FROM PRICE
1921 IOX2

From $104.50

1948 HIF Phd Inhibitor 4

From $115.50

1977 DMOG

From $71.50

2570 FG-2216

From $88.00

2588 FG-4592

From $60.50

3095 MK-8617

From $99.00

3288 Vadadustat

From $88.00

Other Categories

More Categories

Axon Ligands™ for Cell Signaling & Oncology

Axon Ligand™ for Stem Cell Research 

Axon Ligands™ for Epigenetic Research 

Loading...