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SUVN-502
- Masupirdine
- Parent CAS: 701205-60-9
- Soluble in water and DMSO
- MF: C23H32BrN3O9S3
- MW: 670.61
Description
SUVN-502 is a potent, selective and orally active serotonin 6 (5-HT6) receptor antagonist (Ki value of 2.04 nM) with selectivity over 100 target sites which include receptors, enzymes, peptides, growth factors, ion channels, steroids, immunological factors, second messengers, and prostaglandins. Moreover, it has high selectivity over 5-HT2A receptor. SUVN-502 is brain penetrant and a clinical candidate for potential treatment of cognitive disorders.
More Information
| Parent CAS No. | 701205-60-9 |
|---|---|
| Chemical Name | 1-[(2-Bromophenyl)sulfonyl]-5-methoxy-3-[(4-methyl-1-piperazinyl)methyl]-1H-indole bismesylate |
| SMILES | C1(S(=O)(=O)N2C3C=CC(OC)=CC=3C(CN3CCN(C)CC3)=C2)C=CC=CC=1Br.CS(O)(=O)=O.CS(O)(=O)=O |
| MFCD | N.A. |
| InChi | InChI=1S/C21H24BrN3O3S.2CH4O3S/c1-23-9-11-24(12-10-23)14-16-15-25(20-8-7-17(28-2)13-18(16)20)29(26,27)21-6-4-3-5-19(21)22;2*1-5(2,3)4/h3-8,13,15H,9-12,14H2,1-2H3;2*1H3,(H,2,3,4) |
| InChiKey | LOZVXBFXRPRECW-UHFFFAOYSA-N |
| CID | 118142730 |
| Short Description | 5-HT6 antagonist |
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