Bulk Inquiry
MS 245 oxalate
Axon 1849
- Parent CAS: 263384-65-2
Purity:
99%
- Soluble in DMSO
- MF: C19H22N2O3S.C2H2O4
- MW: 448.49
Description
Selective and high affinity 5-HT6 antagonist (Ki = 2.1 nM)
More Information
| Parent CAS No. | 263384-65-2 |
|---|---|
| Chemical Name | 2-(5-methoxy-1-(phenylsulfonyl)-1H-indol-3-yl)-N,N-dimethylethanamine oxalate |
| SMILES | N1(S(C2=CC=CC=C2)(=O)=O)C2=C(C=C(OC)C=C2)C(CCN(C)C)=C1.C(O)(=O)C(O)=O |
| MFCD | N.A. |
| InChi | InChI=1S/C19H22N2O3S.C2H2O4/c1-20(2)12-11-15-14-21(19-10-9-16(24-3)13-18(15)19)25(22,23)17-7-5-4-6-8-17;3-1(4)2(5)6/h4-10,13-14H,11-12H2,1-3H3;(H,3,4)(H,5,6) |
| InChiKey | BLSWAEGCRSFTJG-UHFFFAOYSA-N |
| CID | 6918541 |
| Short Description | 5-HT6 antagonist |
References
- Y Tsai et al. N1-(Benzenesulfonyl)tryptamines as novel 5-HT6 antagonists. Bioorg Med Chem Lett. 2000, 10(20), 2295-2299.
- R Young et al. Effect of the 5-HT(6) serotonin antagonist MS-245 on the actions of (-)nicotine. Pharmacol. Biochem. Behav. 2006, 85(1), 170-1777.
- M Dukat et al. Binding of serotonin and N1-benzenesulfonyltryptamine-related analogs at human 5-HT6 serotonin receptors: receptor modeling studies. J. Med. Chem. 2008, 51, 603.
- RVS Nirogi et al. Novel and potent 5-piperazinyl methyl-N1-aryl sulfonyl indole derivatives as 5-HT6 receptor ligands. ACS Med. Chem. Lett. 2010, 1, 340.
Related Products
| AXON ID | NAME | FROM PRICE |
|---|---|---|
| 1099 | SB 271046 hydrochloride |
From $104.50 |
| 1330 | RO 04-6790 hydrochloride |
From $104.50 |
| 1382 | SB 742457 hydrochloride |
From $88.00 |
| 1575 | 5-HT6 antagonist 29 |
From $99.00 |
| 1710 | WAY 208466 dihydrochloride |
From $132.00 |
| 1927 | SGS 518 |
From $99.00 |
| 2144 | Lu AE58054 hydrochloride |
From $99.00 |
| 2715 | SUVN-502 |
From $115.50 |
Other Categories
Get a Quote for
Loading...