Neurotensin (NT or NTS) is a 13 aminio acid peptide that functions as both a neurotransmitter and a hormone through the activation of the three neurotensin receptors known to date (NT1, NT2, and NT3, GPCR-A7 subfamily). NTS shows a wide range of biological activities.  In the brain, NTS modulates opioid-independent analgesia, the inhibition of food intake and the activity of dopaminergic systems. Consequently, it plays an important role in Parkinson’s disease and the pathogenesis of schizophrenia, the modulation of dopamine neurotransmission, hypothermia, antinociception, and in promoting the growth of cancer cells[1].