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Axon 3698
CAS [226954-04-7]
MF C23H23N5O2MW 401.46
AC-5216 is a selective translocator protein (TSPO; MBR) ligand. AC-5216 showed high affinity for MBRs prepared from rat whole brain (Ki value of 0.297 nM), rat glioma cells (IC50 value of 3.04 nM) and human glioma cells (IC50 value of 2.73 nM), but only negligible affinity for the other main receptors including central benzodiazepine receptors.
KEYWORDS: AC-5216 | Supplier | TSPO ligand | XBDl73 | Emapunil | AC5216 | AC 5216 | XBDl 73 | XBDl-73 | CAS [226954-04-7] | GABA | GABA-A | Ligand | Ion Channels | Anxiety | Depression | Mitochondrial benzodiazepine receptor | MBR
N-Benzyl-N-ethyl-2-(7-methyl-8-oxo-2-phenyl-7H-purin-9(8H)-yl)acetamide
[226954-04-7]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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