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ABBV-075
- Mivebresib
- Soluble in DMSO and EtOH
- MF: C22H19F2N3O4S
- MW: 459.47
Description
ABBV-075 is a highly potent and orally bioavailable BET bromodomain (BRD) inhibitor with a Ki value of 1.5 nM for BRD4 (TR-FRET assay).
More Information
| Parent CAS No. | 1445993-26-9 |
|---|---|
| Chemical Name | N-(4-(2,4-Difluorophenoxy)-3-(6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl)phenyl)ethanesulfonamide |
| SMILES | C1C(C2=CN(C)C(=O)C3NC=CC2=3)=C(OC2C(F)=CC(F)=CC=2)C=CC=1NS(=O)(=O)CC |
| MFCD | MFCD30377200 |
| InChi | InChI=1S/C22H19F2N3O4S/c1-3-32(29,30)26-14-5-7-19(31-20-6-4-13(23)10-18(20)24)16(11-14)17-12-27(2)22(28)21-15(17)8-9-25-21/h4-12,25-26H,3H2,1-2H3 |
| InChiKey | RDONXGFGWSSFMY-UHFFFAOYSA-N |
| CID | 71600087 |
| Short Description | BET inhibitor |
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