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Nateglinide

 - A4166  - Senaglinide
Axon 3641
CAS:  105816-04-4
  • Optical Purity:  Optically pure
  • Soluble in DMSO and EtOH
  • MF:  C19H27NO3
  • MW:  317.42

Description

Nateglinide is an inhibitor of ATP-sensitive K+ channels in pancreatic beta-cells in the presence of glucose and thereby restores first phase insulin response in patients with Type 2 diabetes. Antidiabetic.

More Information

Parent CAS No. 105816-04-4
Chemical Name N-[(trans-4-Isopropylcyclohexyl)carbonyl]-D-phenylalanine
SMILES [C@@H]1(C(C)C)CC[C@@H](C(=O)N[C@H](CC2C=CC=CC=2)C(=O)O)CC1 |&1:0,6,10,r|
MFCD N.A.
InChi InChI=1S/C19H27NO3/c1-13(2)15-8-10-16(11-9-15)18(21)20-17(19(22)23)12-14-6-4-3-5-7-14/h3-7,13,15-17H,8-12H2,1-2H3,(H,20,21)(H,22,23)/t15?,16?,17-/m1/s1
InChiKey OELFLUMRDSZNSF-OFLPRAFFSA-N
CID 5311309
Short Description KATP channel blocker

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