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ProINDY
- TG007
Axon 3540
CAS:
719277-30-2
Purity:
99%
- Soluble in DMSO and EtOH
- MF: C14H15NO3S
- MW: 277.34
Description
ProINDY is the prodrug of INDY (Axon 3538) and is expected to make the molecule more lipophilic and enhance its cell membrane permeability. ProINDY effectively recovered Xenopus embryos from head malformation induced by Dyrk1A overexpression, resulting in normally developed embryos and demonstrating the utility of proINDY in vivo.
More Information
| Parent CAS No. | 719277-30-2 |
|---|---|
| Chemical Name | (Z)-3-Ethyl-2-(2-oxopropylidene)-2,3-dihydrobenzo[d]thiazol-5-yl acetate |
| SMILES | C1C=C2S/C(=CC(=O)C)/N(CC)C2=CC=1OC(=O)C |
| MFCD | N.A. |
| InChi | InChI=1S/C14H15NO3S/c1-4-15-12-8-11(18-10(3)17)5-6-13(12)19-14(15)7-9(2)16/h5-8H,4H2,1-3H3/b14-7- |
| InChiKey | RLEOCVDWLAYGRX-AUWJEWJLSA-N |
| CID | 44633738 |
| Short Description | Dyrk1A inhibitor |
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