Based on 20 reference(s) in Google Scholar 80 100 20

Axon 3412

CAS [897326-30-6]

MW 309.68

  • Purity: 99%
  • Soluble in DMSO



DTHIB is a direct HSF1 inhibitor with a Kd value of 160 nM for DTHIB binding to the HSF1 DNA binding domain (DBD). DTHIB physically engages HSF1 and selectively stimulates degradation of nuclear HSF1. Moreover, DTHIB robustly inhibited the HSF1 cancer gene signature and prostate cancer cell proliferation.

KEYWORDS: DTHIB | supplier | HSF1 inhibitor | CAS [897326-30-6] | DNA-RNA | HSF1 | Inhibitor | Transcription Factors | Prostate cancer

Size Unit Price Stock
10 mg €90.00 In Stock
50 mg €270.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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