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LQZ-7I
Axon 3344
CAS:
195822-23-2
Purity:
99%
- Soluble in DMSO
- MF: C20H14F2N4
- MW: 348.35
Description
LQZ-7I inhibits survivin dimerization, induces survivin degradation in proteasome, and induces apoptosis of prostate cancer cells (IC50 values of 3.1 µM and 4.8 µM against C4-2 cells and PC-3 cells, respectively). LQZ-7I given orally effectively inhibits xenograft tumor growth and induces survivin loss in tumors.
More Information
| Parent CAS No. | 195822-23-2 |
|---|---|
| Chemical Name | N2,N3-Bis(4-fluorophenyl)quinoxaline-2,3-diamine |
| SMILES | C1C=C2N=C(NC3C=CC(F)=CC=3)C(NC3C=CC(F)=CC=3)=NC2=CC=1 |
| MFCD | N.A. |
| InChi | InChI=1S/C20H14F2N4/c21-13-5-9-15(10-6-13)23-19-20(24-16-11-7-14(22)8-12-16)26-18-4-2-1-3-17(18)25-19/h1-12H,(H,23,25)(H,24,26) |
| InChiKey | DKPCKOKYSVPFEB-UHFFFAOYSA-N |
| CID | 468690 |
| Short Description | Survivin inhibitor |
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