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Takinib
- EDHS-206- Soluble in DMSO
- MF: C18H18N4O2
- MW: 322.36
Description
Takinib is a potent and selective TAK1 inhibitor (IC50 value of 0.0095 μM) that induces apoptosis following TNFα stimulation in cell models of rheumatoid arthritis and metastatic breast cancer.
More Information
| Parent CAS No. | 1111556-37-6 |
|---|---|
| Chemical Name | (E)-N1-(1-Propyl-1H-benzo[d]imidazol-2(3H)-ylidene)isophthalamide |
| SMILES | C1C=C2N/C(=NC(=O)C3C=CC=C(C(=O)N)C=3)/N(CCC)C2=CC=1 |
| MFCD | N.A. |
| InChi | InChI=1S/C18H18N4O2/c1-2-10-22-15-9-4-3-8-14(15)20-18(22)21-17(24)13-7-5-6-12(11-13)16(19)23/h3-9,11H,2,10H2,1H3,(H2,19,23)(H,20,21,24) |
| InChiKey | UOZVVPXKJGOFIG-UHFFFAOYSA-N |
| CID | 37750349 |
| Short Description | TAK1 (MAP3K7) inhibitor |
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