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Takinib

 - EDHS-206
Axon 3282
CAS:  1111556-37-6
Purity:  99%
  • Soluble in DMSO
  • MF:  C18H18N4O2
  • MW:  322.36

Description

Takinib is a potent and selective TAK1 inhibitor (IC50 value of 0.0095 μM) that induces apoptosis following TNFα stimulation in cell models of rheumatoid arthritis and metastatic breast cancer.

More Information

Parent CAS No. 1111556-37-6
Chemical Name (E)-N1-(1-Propyl-1H-benzo[d]imidazol-2(3H)-ylidene)isophthalamide
SMILES C1C=C2N/C(=NC(=O)C3C=CC=C(C(=O)N)C=3)/N(CCC)C2=CC=1
MFCD N.A.
InChi InChI=1S/C18H18N4O2/c1-2-10-22-15-9-4-3-8-14(15)20-18(22)21-17(24)13-7-5-6-12(11-13)16(19)23/h3-9,11H,2,10H2,1H3,(H2,19,23)(H,20,21,24)
InChiKey UOZVVPXKJGOFIG-UHFFFAOYSA-N
CID 37750349
Short Description TAK1 (MAP3K7) inhibitor

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