Based on 20 reference(s) in Google Scholar 80 100 20

Axon 3216

CAS [2242470-43-3]

MF C23H20N2O2
MW 356.42

  • Purity: 99%
  • Soluble in 0.1N HCl(aq) and DMSO



DCZ0415 is an AAA-ATPase TRIP13 inhibitor with a Kd value of 2.42 μM. DCZ0415 induced antimyeloma activity in vitro (IC50 values of 1.0-10 μM in multiple myeloma cell lines), in vivo, and in primary cells derived from drug-resistant patients with myeloma. Moreover, DCZ0415 impaired nonhomologous end joining repair and inhibited NF-κB activity.

KEYWORDS: DCZ0415 | supplier | TRIP13 inhibitor | DCZ 0415 | DCZ-0415 | CAS [2242470-43-3] | ATP | ATPase (AAA+) | Inhibitor | Enzymes | Multiple myeloma

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5 mg €85.00 In Stock
25 mg €290.00 In Stock
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Size Unit Price Stock
2 x 5 mg €140.00 In Stock
2 x 25 mg €500.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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