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Axon 3200
CAS [2222635-15-4]
MF C26H28F3N7O2MW 527.54
DCLK1-IN-1 is a potent, selective and orally bioavailable DCLK1/2 inhibitor. DCLK1-IN-1 exhibits binding assay IC50 values of 9.5 nM and 31 nM for DCLK1 and DLCK2, respectively. Moreover, DCLK1-IN-1 exhibits kinase assay IC50 values of 57.2 nM and 103 nM for DCLK1 and DLCK2, respectively.
KEYWORDS: DCLK1-IN-1 | supplier | DCLK1/2 inhibitor | FMF-03-146-1 | CAS [2222635-15-4] | [2503125-35-5] | Non Selective | DCLK | Inhibitor | Enzymes | Doublecortin like kinase | Colorectal cancer | Gastric cancer | Pancreatic ductal adenocarcinoma | PDAC
2-(2-Methoxy-4-(4-methylpiperazin-1-yl)phenylamino)-11-methyl-5-(2,2,2-trifluoroethyl)-5H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6(11H)-one
[2222635-15-4]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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