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Axon 3195
CAS [2152628-33-4]
MF C29H31N7O3MW 525.60
Selpercatinib is a potent, highly selective, ATP-competitive RET inhibitor with an IC50 value of 4 nM (KIF5B-RET). Selpercatinib demonstrated potent and selective anti-RET activity preclinically against human cancer cell lines harboring endogenous RET gene alterations.
KEYWORDS: Selpercatinib | supplier | RET inhibitor | LOXO-292 | LOXO292 | LOXO 292 | CAS [2152628-33-4] | GDNF | RET | Inhibitor | Receptors
6-(2-Hydroxy-2-methylpropoxy)-4-(6-(6-((6-methoxypyridin-3-yl)methyl)-3,6-diazabicyclo[3.1.1]heptan-3-yl)pyridin-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile
[2152628-33-4]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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