Apcin

Based on 16 reference(s) in Google Scholar 8 10 16

Axon 3194

CAS [300815-04-7]

MF C13H14Cl3N7O4
MW 438.65

  • Purity: 99%
  • Soluble in DMSO

Apcin

Description

Apcin is an inhibitor of APC/C-Cdc20. Apcin binds to Cdc20 and competitively inhibits the ubiquitylation of D-box-containing substrates. Apcin causes either net APC/C inhibition, prolonging mitosis when spindle assembly checkpoint (SAC) activity is low, or net APC/C activation, shortening mitosis when SAC activity is high.

KEYWORDS: Apcin | supplier | APC/C-Cdc20 inhibitor | CAS [300815-04-7] | Securin | B type cyclins | Ubiquitin Ligase (E3; other) | Inhibitor | Enzymes | Anaphase-promoting complex/cyclosome | Mitotic checkpoint complex | MCC | Mitosis | Mitotic exit | APC inhibitor

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10 mg €110.00 In Stock
50 mg €400.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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