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Pomalidomide
- CC-4047
Axon 3166
CAS:
19171-19-8
Purity:
99%
- Soluble in DMSO
- MF: C13H11N3O4
- MW: 273.24
Description
Pomalidomide is a potent inhibitor of TNFα with an IC50 value of 13 nM (LPS stimulated human PBMC). Moreover, Pomalidomide appears to be a remarkable agent in the care of myelofibrosis and multiple myeloma. Immunomodulator.
More Information
| Parent CAS No. | 19171-19-8 |
|---|---|
| Chemical Name | 4-Amino-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione |
| SMILES | C1C(N)=C2C(=O)N(C3C(=O)NC(=O)CC3)C(=O)C2=CC=1 |
| MFCD | MFCD12756407 |
| InChi | InChI=1S/C13H11N3O4/c14-7-3-1-2-6-10(7)13(20)16(12(6)19)8-4-5-9(17)15-11(8)18/h1-3,8H,4-5,14H2,(H,15,17,18) |
| InChiKey | UVSMNLNDYGZFPF-UHFFFAOYSA-N |
| CID | 134780 |
| Short Description | TNFα inhibitor |
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