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Centhaquin
- Centhaquine
- Soluble in 0.1N HCl(aq) and DMSO
- MF: C22H25N3
- MW: 331.45
Description
Centhaquin is a centrally acting hypotensive agent predominantly inhibiting the neuronal norepinephrine release.
More Information
| Parent CAS No. | 57961-90-7 |
|---|---|
| Chemical Name | 2-(2-(4-m-Tolylpiperazin-1-yl)ethyl)quinoline |
| SMILES | C1C=C2C=CC(CCN3CCN(C4C=CC=C(C)C=4)CC3)=NC2=CC=1 |
| MFCD | MFCD01685420 |
| InChi | InChI=1S/C22H25N3/c1-18-5-4-7-21(17-18)25-15-13-24(14-16-25)12-11-20-10-9-19-6-2-3-8-22(19)23-20/h2-10,17H,11-16H2,1H3 |
| InChiKey | UJNWGFBJUHIJKK-UHFFFAOYSA-N |
| CID | 162163 |
| Short Description | Hypotensive agent |
References
- M Bhatnagar et al. Effect of Centhaquine on Spontaneous and Evoked Norepinephrine Release From Isolated Perfused Rabbit Heart. Arzneimittelforschung. 1985;35(4):693-7.
- RC Srimal et al. Pharmacological Studies on 2-(2-(4-(3-methylphenyl)-1-piperazinyl)ethyl) Quinoline (Centhaquin). I. Hypotensive Activity. Pharmacol Res. 1990;22(3):319–329.
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