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BRD0539

Axon 3009
CAS:  1403838-79-8
  • Optical Purity:  99% e.e.
  • Soluble in DMSO and EtOH
  • MF:  C25H25FN2O3S
  • MW:  452.54

Description

BRD0539 is a reversible and cell-permeable inhibitor of SpCas9 with an apparent IC50 value of 22 μM (in vitro DNA cleavage assay).

More Information

Certificate of Analysis

Material Safety Data Sheet

Parent CAS No. 1403838-79-8
Chemical Name ((3aR,4R,9bR)-8-(2-Fluorophenyl)-1-tosyl-2,3,3a,4,5,9b-hexahydro-1H-pyrrolo[3,2-c]quinolin-4-yl)methanol
SMILES C1C=C(F)C(C2C=C3[C@@H]4N(S(C5C=CC(C)=CC=5)(=O)=O)CC[C@@H]4[C@H](CO)NC3=CC=2)=CC=1 |&1:8,22,23,r|
MFCD N.A.
InChi InChI=1S/C25H25FN2O3S/c1-16-6-9-18(10-7-16)32(30,31)28-13-12-20-24(15-29)27-23-11-8-17(14-21(23)25(20)28)19-4-2-3-5-22(19)26/h2-11,14,20,24-25,27,29H,12-13,15H2,1H3/t20-,24+,25-/m1/s1
InChiKey CZOIXFMISSBIJL-DCEDVJGZSA-N
CID 54666326
Short Description Cas9 inhibitor

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