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TH 257

Axon 2973
CAS:  2244678-29-1
Purity:  99%
  • Soluble in DMSO
  • MF:  C24H26N2O3S
  • MW:  422.54

Description

TH 257 is a selective allosteric inhibitor of LIMK1 and LIMK2 with IC50 values of 84 nM and 39 nM, respectively. A negative control is also available: TH 263 (Axon 2974).

More Information

Parent CAS No. 2244678-29-1
Chemical Name N-Benzyl-N-butyl-4-(N-phenylsulfamoyl)benzamide
SMILES C1C=C(C(=O)N(CCCC)CC2C=CC=CC=2)C=CC=1S(=O)(=O)NC1C=CC=CC=1
MFCD N.A.
InChi InChI=1S/C24H26N2O3S/c1-2-3-18-26(19-20-10-6-4-7-11-20)24(27)21-14-16-23(17-15-21)30(28,29)25-22-12-8-5-9-13-22/h4-17,25H,2-3,18-19H2,1H3
InChiKey VNCIWNGCMAKKEO-UHFFFAOYSA-N
CID 137796294
Short Description LIMK1/2 inhibitor

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