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FM19G11
- Soluble in DMSO
- MF: C23H17N3O8
- MW: 463.4
Description
FM19G11 is an HIFα inhibitor with an IC50 value of 80 nM. FM19G11 inhibits HIFα proteins that repress target genes of the two α subunits, in various tumor cell lines as well as in adult and embryonic stem cell models from rodents and humans, respectively.
More Information
| Parent CAS No. | 329932-55-0 |
|---|---|
| Chemical Name | 2-Oxo-2-p-tolylethyl 3-(2,4-dinitrobenzamido)benzoate |
| SMILES | C1C([N+]([O-])=O)=C(C(=O)NC2C=CC=C(C(=O)OCC(=O)C3C=CC(C)=CC=3)C=2)C=CC=1[N+]([O-])=O |
| MFCD | MFCD01174289 |
| InChi | InChI=1S/C23H17N3O8/c1-14-5-7-15(8-6-14)21(27)13-34-23(29)16-3-2-4-17(11-16)24-22(28)19-10-9-18(25(30)31)12-20(19)26(32)33/h2-12H,13H2,1H3,(H,24,28) |
| InChiKey | XVUOIWIIQVGWAJ-UHFFFAOYSA-N |
| CID | 1730746 |
| Short Description | HIFα inhibitor |
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