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SGC707
Axon 2945
CAS:
1687736-54-4
Purity:
99%
- Soluble in DMSO
- MF: C16H18N4O2
- MW: 298.34
Description
SGC707 is a first-in-class, potent, selective and cell-active allosteric inhibitor of protein arginine methyltransferase 3 (PRMT3) with an IC50 value of 31 nM. SGC707 is bioavailable and suitable for animal studies.
More Information
| Parent CAS No. | 1687736-54-4 |
|---|---|
| Chemical Name | 1-(Isoquinolin-6-yl)-3-(2-oxo-2-(pyrrolidin-1-yl)ethyl)urea |
| SMILES | C12C=NC=CC=1C=C(NC(=O)NCC(N1CCCC1)=O)C=C2 |
| MFCD | N.A. |
| InChi | InChI=1S/C16H18N4O2/c21-15(20-7-1-2-8-20)11-18-16(22)19-14-4-3-13-10-17-6-5-12(13)9-14/h3-6,9-10H,1-2,7-8,11H2,(H2,18,19,22) |
| InChiKey | DMIDPTCQPIJYFE-UHFFFAOYSA-N |
| CID | 90642938 |
| Short Description | PRMT3 inhibitor |
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