IBP, 4- - NSC 667672

Based on 16 reference(s) in Google Scholar 8 10 16

Axon 2919

CAS [155798-08-6]

MF C19H21IN2O
MW 420.29

  • Purity: 98%
  • Soluble in DMSO
Recently added

IBP, 4-

Description

4-IBP is a selective sigma-1 (σ-1) agonist with Ki values of 1.70 nM and 25.2 nM for σ-1 and σ-2 receptor subtypes, respectively. Activating the σ-1 receptor with noncytotoxic doses of 4-IBP decreases the migration levels of various types of cancer cells, including C32 melanoma, U373-MG glioblastoma, A549 NSCLC, and PC3 prostate cancer cells. Moreover, 4-IBP sensitizes these cancer cells in vitro and in vivo to cytotoxic insults of proapoptotic and proautophagic drugs.

KEYWORDS: 4-IBP | supplier | Sigma-1 agonist | NSC 667672 | 4IBP | 4 IBP | NSC667672 | NSC-667672 | CAS [155798-08-6] | Sigma Receptor Substrates | Sigma-1 | Antagonist | Receptors

Order
Size Unit Price Stock
10 mg €90.00 In Stock
50 mg €330.00 In Stock
Need more? Bulk Inquiry

The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

Please wait...