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PRE-084 hydrochloride
Axon 3063
- Parent CAS: 138847-85-5
Purity:
99%
- Soluble in water and DMSO
- MF: C19H27NO3.HCl
- MW: 353.88
Description
PRE-084 hydrochloride is a highly selective sigma-1 (σ-1) agonist with a Ki value of 2.2 nM.
More Information
| Parent CAS No. | 138847-85-5 |
|---|---|
| Chemical Name | 2-Morpholinoethyl 1-phenylcyclohexanecarboxylate hydrochloride |
| SMILES | C1C=C(C2(CCCCC2)C(=O)OCCN2CCOCC2)C=CC=1.Cl |
| MFCD | MFCD00673883 |
| InChi | InChI=1S/C19H27NO3.ClH/c21-18(23-16-13-20-11-14-22-15-12-20)19(9-5-2-6-10-19)17-7-3-1-4-8-17;/h1,3-4,7-8H,2,5-6,9-16H2;1H |
| InChiKey | QUJWFJNHTBKCLU-UHFFFAOYSA-N |
| CID | 11314197 |
| Short Description | Sigma-1 agonist |
References
- TP Su et al. Sigma compounds derived from phencyclidine: identification of PRE-084, a new, selective sigma ligand. J Pharmacol Exp Ther. 1991 Nov;259(2):543-50.
- T Maurice et al. The attenuation of learning impairments induced after exposure to CO or trimethyltin in mice by sigma (sigma) receptor ligands involves both sigma1 and sigma2 sites. Br J Pharmacol. 1999 May;127(2):335-42.
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