Dolutegravir - GSK 1349572 | Soltegravir | Tivicay

Based on 130 reference(s) in Google Scholar 8 10 130

Axon 2855

CAS [1051375-16-6]

MF C20H19F2N3O5
MW 419.38

Purity: 99%
Soluble in DMSO

Dolutegravir

Description

Dolutegravir is an HIV integrase inhibitor with potent in vitro anti-HIV activity (IC50 value of 0.51 nM), an in vitro resistance profile different from those of other integrase inhibitors, and favorable preclinical safety and pharmacokinetics.

KEYWORDS: Dolutegravir | supplier | HIV integrase inhibitor | GSK 1349572 | Soltegravir | Tivicay | GSK1349572 | GSK-1349572 | CAS [1051375-16-6] | DNA | HIV | Inhibitor | Enzymes

S Min et al. Pharmacokinetics and safety of S/GSK1349572, a next-generation HIV integrase inhibitor, in healthy volunteers. Antimicrob Agents Chemother. 2010 Jan;54(1):254-8.

S Hare et al. Structural and functional analyses of the second-generation integrase strand transfer inhibitor dolutegravir (S/GSK1349572). Mol Pharmacol. 2011 Oct;80(4):565-72.

Immunology HIV

HIV integrase inhibitor

Chemical name

(4R,12aS)-N-(2,4-Difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-[1,3]oxazino[3,2-d]pyrido[1,2-a]pyrazine-9-carboxamide

Parent CAS No.

[1051375-16-6]

Order

Size	Unit Price	Stock
5 mg	€135.00	In Stock
25 mg	€485.00	In Stock

Need more? Bulk Inquiry

Related Products

Axon ID	Name	Description
1534	Dapivirine	NNRT inhibitor	€80.00
1815	Delavirdine	NNRT inhibitor (HIV-1)	€90.00
2173	CX 5461	Inhibitor of RNA Polymerase I (RNAP1)	€120.00
2208	Gallic acid	Multi-affinity drug. Antioxidant.	€50.00
2301	BIBR 1532	Potent and selective telomerase inhibitor inducing senescence in human cancer cells.	€70.00
2462	BMH 21	Inhibitor of RNA Polymerase I (RNAP1)	€95.00
3120	Raltegravir	Potent, selective and orally bioavailable HIV integrase inhibitor	€90.00
3483	NBD-556	HIV-1 entry inhibitor; gp120-CD4 interaction blocker	€70.00

Customer Support

Customer Services

About Axon Medchem

Contact Us

Dolutegravir - GSK 1349572 | Soltegravir | Tivicay

Description

Chemical name

Parent CAS No.

Customer Support

About Axon Medchem

Download Product Catalog

Follow Us

Customer Support

Customer Services

About Axon Medchem

Contact Us

Dolutegravir - GSK 1349572 | Soltegravir | Tivicay

Description

Chemical name

Parent CAS No.

Related Products

Customer Support

About Axon Medchem

Download Product Catalog

Follow Us

Send us a message

Contact Us