ThioLox - Thiophene A9

Based on 3 reference(s) in Google Scholar 8 10 3

Axon 2844

CAS [1202193-89-2]

MF C15H18N2OS
MW 274.38

  • Purity: 99%
  • Soluble in DMSO

ThioLox

Description

Inhibitor of 15-lipoxygenase-1 (15-LOX-1) with both anti-inflammatory and neuroprotective properties (IC50 value of 12 µM). Ex vivo biological evaluation in precision-cut lung slices (PCLS) showed inhibition of pro-inflammatory gene expression and in vitro studies on neuronal HT-22 cells showed a strong protection against glutamate toxicity for this 15-LOX-1 inhibitor.

KEYWORDS: Thiolox | supplier | Lipoxygenase inhibitor | CAS [1202193-89-2] | Fatty acid (Arachidonic acid) | LOX | Inhibitor | Enzymes

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Size Unit Price Stock
5 mg €120.00 In Stock
25 mg €420.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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