VH298

Based on 2 reference(s) in Google Scholar 8 10 2

Axon 2810

CAS [2097381-85-4]

MF C27H33N5O4S
MW 523.65

  • Purity: 98%
  • Soluble in DMSO

VH298

Description

VH298 is a potent and selective VHL inhibitor (Kd value of 80-90 nM) that stabilizes HIF-α and elicits a hypoxic response via the blockade of the VHL:HIF-α protein–protein interaction downstream of HIF-α hydroxylation by PHD enzymes.

KEYWORDS: VH298 | supplier | VHL inhibitor  | VH-298 | VH 298 | CAS [2097381-85-4] | Smad | Ubiquitin Ligase (E3; VHL) | Inhibitor | Enzymes | von-Hippel-Lindau | prolyl hydroxylase | PHD

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Size Unit Price Stock
10 mg €135.00 In Stock
50 mg €505.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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