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Axon 2755
CAS [1206170-62-8]
MF C17H20N6OMW 324.38
Potent and selective Mps1 (TTK) kinase inhibitor (IC50 value of 6.4 nM) with good cellular activity, pharmacokinetic properties and efficacy in the A549 lung cancer xenograft model. Additionally, TC Mps1 12 suppressed the growth of hepatocellular carcinoma cells via the accumulation of chromosomal instability.
KEYWORDS: TC Mps1 12 | supplier | Mps1 inhibitor | CAS [1206170-62-8] | Non Selective (Mitotic Spindle Checkpoint) | MPS1 Kinase | Inhibitor | Enzymes | TTK
4-(4-Amino-6-(tert-butylamino)-5-cyanopyridin-2-ylamino)benzamide
[1206170-62-8]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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