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Axon 2744
CAS [916141-36-1]
MF C27H26N4O2SMW 470.59
TCS1102 is a potent and selective dual orexin receptor antagonist (Ki values of 3 and 0.2 nM for hOX1R and hOX2R, respectively). Moreover, TCS1102 demonstrated in vivo central activity when dosed peripherally in a pharmacodynamic model of orexin activity.
KEYWORDS: TCS1102 | supplier | OX1/2 antagonist | TCS 1102 | TCS-1102 | DORA-1 | DORA1 | DORA 1 | CAS [916141-36-1] | Orexin | Orexin (OX) | Antagonist | Receptors
(S)-N-(Biphenyl-2-yl)-1-(2-(1-methyl-1H-benzo[d]imidazol-2-ylthio)acetyl)pyrrolidine-2-carboxamide
[916141-36-1]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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